Diabetic Neuropathy Assessment through Corneal Confocal Microscopy – Keynote Lecture

Confocal microscopy of the cornea is the first method that allows for an in-vivo visualization and quantification of terminal trigeminal nerve fibers. Under physiological conditions, the system captures nerve structures with a total length of 20 mm/mm2 in the sub-basal plexus. In his keynote lecture to be presented on Thursday, October 1, 2015, Rudolf Guthoff will demonstrate that diabetic patients present with a significant reduction in nerve fiber density even at the point of first diagnosis. Confocal in-vivo microscopy of the cornea does therefore arguably present the most sensitive method for capturing diabetic neuropathy.

Professor Dr. med. Rudolf Guthoff’s research foci include medical imaging in ophthalmology. Between 1992 and 2014, Professor Guthoff served as director of the Rostock University Eye Clinic. It was here that he developed confocal in-vivo microscopy of the human cornea. Rudolf Guthoff was the faculty director at Rostock University for four years. In 2001, he served as president of the German Ophthalmology Society DOG. He was elected “Professor of the Year” in 2006 and elected chairman of the Leopoldina in 2011. Rudolf Guthoff is spokesman for the International Ophthalmology Section within the DOG. Since 2014, he has been the acting director of the Institute for Biomedical Engineering Rostock.